CD274 and non-small cell lung carcinoma: In one study of 249 patients with NSCLC, renal cell carcinoma, and urothelial carcinoma treated with MoAbs against PD-1/PD-L1, a shotgun sequencing identified an overrepresentation of bacterial genera including Akkermansia muciniphila in responders to PD-1 inhibition compared with non-responders.