Regarding the CX3CL1 effect on il1β expression in microglial cells after brain ischemia, it induced an increase in the expression of this cytokine 24 h after ischemia while it had an opposite effect after 72 h from ischemic damage (n = 4 mice per group, ∗∗p < 0.001 ∗p > 0.05; Student’s t-test), contrary to what observed for CD11B+ cells (see Figures 4B,D). Here, CX3CL1 is linked to brain ischemia.