Up-regulation ofBRCA1, as a tumor-suppressor gene in the non-mutatedstate, is contradictory to these findings to some extent,and significance of that needs to be further investigated.Utilizing western blot, a strong correlation was determinedbetween alterations of gene expression and correspondingprotein content in VIM/Vimentin, RAB27A/Rab-27aand MAPK1/MAPK1. Here, MAPK1 is linked to neoplasm.