The percentage of NKG2D+ NK cells from healthydonors was more than DLBCL patients in the absenceof exosomes or in the presence of IL-2/IL-15, plasma-derived exosome of refractory/relapsed DLBCL patients,plasma-derived exosome of refractory/relapsed DLBCLpatients plus IL-2/IL-15 and plasma-derived exosomeof responsive DLBCL patients (P<0.05, P<0.01 andP<0.001, ANOVA test). Here, KLRK1 is linked to diffuse large B-cell lymphoma.