Some studies showed the SOCS-1 and INPP5D aretwo direct targets of hsa-miR-155-5p in many cell types.To determine whether plasma-derived exosomes ofresponsive or refractory/relapsed DLBCL patients areable to alter expression levels of SOCS-1 and INPP5D, weexamined these expression levels in NK cells of healthydonors and DLBCL patients. This evidence concerns the gene INPP5D and diffuse large B-cell lymphoma.