The percentage of NK cells expressing CD16, CD69 andNKG2D was determined by flow-cytometer in the absence orpresence of IL-2/IL-15 and 20 μg of plasma-derived exosome ofDLBCL patients in each group (healthy donors and responsiveor refractory/relapsed patients with DLBCL) after 24 hours ofculture in a FBS-free or AB serum-free media (Fig .4I). This evidence concerns the gene FCGR3A and diffuse large B-cell lymphoma.