PLCG1 and breast carcinoma: Phosphorylation on tyrosine residue 783 of PLCγ1activates this enzyme to contribute critical roles in cellmigration, invasion and spreading in cancers (7, 9,10).By studying PLCγ1 and the corresponding role in tumorslike breast carcinomas, it was clarified that extremeexpression of PLCγ1 facilitates cancer metastasis, whileblocking this protein will halt the cancer expansion (7,11).