Taken together, the present study suggests thatevaluation of cytosolic phospholipase A2 deltaconcentration, alone or in consolidation with otherconventional markers, may provide critical knowledgefor the early noninvasive disclosure of HCC.Moreover, cytosolic phospholipase A2 delta might alsobe served as a potential target to find out the status andprogression of liver cancer. The gene discussed is PLA2G4A; the disease is liver cancer.