AHR and brain infarction: The aryl hydrocarbon receptor (AHR) antagonist 6,2′,4′-trimethoxyflavone (TMF)-treated wild-type (WT) and AHR conditional knockout (AHRcKO) mice exhibited a reduction in brain infarction compared with the vehicle-treated WT and AHRflx/flx mice, respectively (Fig. 1a, b).