SOX2 and Stroke: To further explore whether AHR antagonist TMF treatment and nestin+ cell-specific AHRcKO affect neural stem cells (NSCs) and neural progenitor cells (NPCs) in adult stroke mice, we examined the number of sex determining region Y-box 2 (SOX2)-, GFAP-, and doublecortin (DCX)-expressing cells, and poststroke bromodeoxyuridine (BrdU)-labeled cells at the neurogenic subventricular zone (SVZ) and subgranular zone (SGZ) (Fig. 4a).