During apoptosis, TNPO2 inhibits apoptosis in Hela cells.13 Recent studies have demonstrated that TNPO2 is highly expressed in malignant pleural mesothelioma (MPM) tissues and cells, which might represent a new cancer gene.14 However, the role played by TNPO2 in gastric cancer has not been previously elucidated or reported. This evidence concerns the gene TNPO2 and cancer.