Specifically, according to the expression of PD‐L1 on tumor cells and tumor‐infiltrating lymphocytes (TILs), TMIT classification has been recently proposed by Teng et al,15 including TMIT I adaptive immune resistance (PD‐L1 positive and high TIL), TMIT II immune ignorance (PD‐L1 negative and low TIL), TMIT III intrinsic induction (PD‐L1 positive and low TIL), and TMIT IV immune tolerance (PD‐L1 negative and high TIL). Here, CD274 is linked to neoplasm.