T cells, NK cells, and γδ T cells are the main producers of IFN‐γ during CHMI, and the proportion of IFN‐γ+ cells in each subset increases in response to parasitemia.56, 80 Of these, T cells constitute the majority of pRBC‐specific IFN‐γ+ producing cells,56, 80 and pRBC‐specific IFN‐γ+ T cells remain stable even four months postchallenge while the pRBC‐targeting IFN‐γ+ NK cell population wanes relatively quickly. The gene discussed is IFNG; the disease is parasitic infectious disease.