The positive HER2 ratios were 27.3% (3/11) for grade 2 and 8.7% (2/23) for grade 3 in the primary cancer specimens, and 28.6% (2/7) for grade 2 and 7.4% (2/27) for grade 3 in the LN metastasis specimens (Table 3). The gene discussed is ERBB2; the disease is cancer.