Moreover, three cholesterol related variants were identified: rs6180 variant in the GHR gene [OMIM:143890], a heterozygous risk factor for familial hypercholesterolemia; rs5370 variant in the EDN1 gene identified with heterozygous association with High Density Lipoprotein (HDL) cholesterol levels; and rs5882 variant in the CETP gene [OMIM:143470], a heterozygous SNP associated with Hyperalphalipoproteinemia. This evidence concerns the gene EDN1 and hyperalphalipoproteinemia.