GRHL2 and breast carcinoma: In breast cancer samples B7 and B13, we detected in concordance with the ATAC-seq data (Supplementary Data 2; Supplementary Data 4) increased accessibility for GRHL2, FOXA1, and ZNF121 (Supplementary Fig. 5), a zinc finger protein, which was recently implicated in regulation of cell proliferation and breast cancer development27.