IL17A and neoplasm: In multiple preclinical models, including 4T1 tumors, tumor-infiltrating IL-17-producing γδT and Th17 cells show potent protumoral functions through their recruitment or interactions with other immune cells such as neutrophils, MDSCs, M2 macrophages, and Treg cells, which can lead to immune suppression, enhanced angiogenesis, and metastasis39–43.