For example, several immune abnormalities have been reported in SLE patients, including complement deficiency [27], complement receptor deficiency [9, 28], defective chemotaxis and phagocytosis [7], decreased production of interleukin-8 by polymorphonuclear leukocytes [29], and impaired activity of T-helper cells against viral antigens [30]. The gene discussed is CXCL8; the disease is systemic lupus erythematosus.