The line ATC7-L, derived from an adrenal fasciculata tumour (induced by targeted expression of SV40 large T antigen (Sahut-Barnola et al., 2000)), produces corticosterone in response to physiological ACTH concentrations, as well as episodic secretion in response to ACTH pulses (Ragazzon et al., 2006; Hazell et al., 2019). Here, POMC is linked to neoplasm.