Similarly, in recent studies of HCC, miR‐211 and miR34a levels inversely correlated with SATB2 levels and modulated cancer cell progression and metastasis.25, 26 Our data demonstrate that SATB2 can regulate cell migration and invasion by modulating EMT‐related genes (cadherins) and transcription factors (Snail, Slug and Zeb1). Here, SATB2 is linked to hepatocellular carcinoma.