However, TGF-β2 is only partially responsible for the ANGPTL4 induction by ACM, as tumor cell ANGPTL4 induction in the full ACM was about 1.6-fold compared with that in the TGF-β2-depleted ACM, whereas it was about threefold compared with that in DMEM. The gene discussed is TGFB2; the disease is neoplasm.