We found that high ITGB4 expression was associated with elder onset age (Figure 1F), proximal tumor location (Figure 1G), and MSH status (Figure 1H) in GSE39582, with M stage in GSE41258, and with MSH status in TCGA colon cancer dataset (Figure 1I) (Table S1). The gene discussed is ITGB4; the disease is malignant colon neoplasm.