As ITGB4 functions by forming dimer with ITGA6, we also investigated the effects of ITGA6 expression on prognostic value of ITGB4 expression with the data from datasets GSE41258 and GSE72970 and found ITGA6 expression did not influence the association of ITGB4 expression with prognosis in colon cancer (data not shown). This evidence concerns the gene ITGA6 and malignant colon neoplasm.