In addition, increased CD69 expression on CD155Bi-Ab-ATCs over their unarmed ATC counterparts after co-culture with bladder cancer cells were detected by FACS analysis.CD69, an early activation marker of T-cell, is regarded as a target for the treatment of immune-mediated diseases and crucial for immune responses 36. The gene discussed is CD69; the disease is Ehlers-Danlos syndrome, musculocontractural type.