Further, mutations corresponding to G636-FGFR4 include D647N-FGFR1 in lung cancer, D650H-FGFR2 in stomach cancer, D650Y-FGFR2 in endometrial cancer and D641N-FGFR3 in bladder cancer31–34. This evidence concerns the gene FGFR2 and gastric neoplasm.