To this end, we studied effects of specific deletion of Mcl-1 in the lysozyme M expressing myeloid subsets neutrophils and macrophages on early and advanced atherosclerosis using bone marrow transplantation of Mcl-1fl/fl LysMCre or wild-type (WT) bone marrow into low density lipoprotein receptor-null (LDLr−/−) mice. Here, MCL1 is linked to atherosclerosis.