As the ratio of CD8+ to CD4+FoxP3+ T regs in the tumor microenvironment is highly associated with the T cell–based immune response against tumor after treatment, we speculated that tumor-infiltrating T cells, including both CD8+ and CD4+ T reg cells, played an important role in SLR14-driven antitumor immunity. The gene discussed is FOXP3; the disease is neoplasm.