Moreover, patients had worse prognosis with high PI or low AI (P = 0.013 for ADC, Fig. 4e; P = 0.022 for SCC, Fig. 4c, respectively); also, lung ADC patients with high Mcl-1 expression and PI, or with high Mcl-1 expression and low AI had significantly lower overall survival rates than patients with any other patterns of Mcl-1/PI/AI (P = 0.000, Fig. 5c; P = 0.037, Fig. 5d). The gene discussed is MCL1; the disease is AIDS dementia complex.