One previous study reports that Circ-SMARCA5 is involved in the regulation of cell cycle and alterations of chromatin structures, and dysregulation of SMARCA5 gene is presented in CD34+ hematopoietic progenitors of hematological malignancy, and we speculated that Circ-SMARCA5 might participate in etiology and work as a potential biomarker of MM, a typical hematological malignancy [11, 15]. This evidence concerns the gene SMARCA5 and Miyoshi myopathy.