TP53 and neoplasm: Besides mutated TP53 (p = 0.019), factors associated with a more advanced tumor stage: higher N, M, and R as well as the UICC stage reached the level of positive correlation with overall model success (p-values of 0.011, 0.008, 0.026, and 0.023, respectively) in addition to higher grading (p = 0.006 for any model success), which was significant for the primary cell line but not PDX success.