HIF1A and cancer: Similarly, it has been reported that hypoxia also increases glycogen synthesis mediated by enhanced HIF-1α stabilization in cancer (mouse hepatoma HePaC1; breast MCF-7 and MDA-MB231; colon LS174 and BE; and kidney RCCA) and noncancer (lung CCL39; mouse embryonic fibroblasts (MEFs); mouse skeletal myoblast C2C12; myotubes; mouse hepatocytes) cells: HIF-1a regulation of glycogen metabolism in cancer cells under normoxia has not been explored.