SLC2A1 and carcinoma: Mutated KRASG13D overexpression increases the mRNA and protein contents of GLUT1 and HKII through the Raf/MRK/Erk/c-MYC and Pi3K/Akt pathways [68,69] in human colon HTC116 and DLD1 carcinomas (Figure 1, Table 2), as well as in HRAS-transformed embryonic NIH 3T3 fibroblasts and human breast epithelial MCF10A cells.