As for nonsquamous NSCLC, in a phase 2 trial evaluating the addition of neoadjuvant BEV to CHT, Chaft et al. found that no patient (0 out of 10) with KRAS mutation showed a pathological response to neoadjuvant BEV/CHT, in comparison to 11 of 31 KRAS WT patients [29]. This evidence concerns the gene KRAS and non-small cell lung carcinoma.