FGF2 and cancer: On the other hand, Tetrac induced a significant increase in FAF1, CASP8AP2, DFFA, and CASP2 mRNA levels and inhibition of the angiogenic and metastatic effects of vascular endothelial growth factor (VEGFR) and basic fibroblast growth factor (bFGF) in cancer [151,152] (Figure 5B).