CASP9 and Alzheimer disease: Repeated Iso exposures led to a near three-fold increase in caspase 9 intensity in 3xTg-AD neonates (Fig 3A and 3C; p < 0.02), whereas neonatal NonTg mice only trended toward an increase in caspase-9 (Fig 3A and 3C; p > 0.05).