SNCA and Parkinson disease: In our previous studies, neonatal rats treated daily per o.s. for 2 weeks with permethrin (34 mg/kg body weight) developed the three pathological hallmarks of PD: namely loss of dopaminergic neurons in the substantia nigra, increase of free and aggregated alpha-synuclein protein levels reminiscent of Lewy bodies and motor and non-motor symptoms correlated with PD [1], [2], [3], [4].