However, when we performed the subgroup analyses based on regions and tumor types of the IL‐10 level (Table 3), we found that the circulating levels of IL‐10 in Asian patients (pooled SMD 0.48 [95% CI: 0.24‐0.73; P = .000]) and mixed gliomas (pooled SMD 0.50 [95% CI: 0.19‐0.81; P = .001]) were significantly higher than in healthy controls. The gene discussed is IL10; the disease is neoplasm.