CD4 and neoplasm: The combination of IL‐7 and IL‐12 synergistically enhances the anti‐tumour immunity by promoting CD3+ T‐cell and CD4+ T‐cell proliferation.33 Also, the combination of IL‐7 and IL‐12 synergistically enhances the anti‐tumour immunity by promoting the proliferation and anti‐tumour function of cytotoxic CD8+ T cells.34 Most of the previous studies on the anti‐tumour activity were focused on the immune responses.