KLK3 and posterior cortical atrophy: Several studies have highlighted the association between KLK3 gene polymorphism and susceptibility to PCa (Chen & Xin, 2017; Ding et al., 2018; Motamedi et al., 2019), and Zambon et al. (2012) successfully combined the KLK3 genetics analysis and free-to-total PSA ratio for PCa diagnosis.