PVT1 and neoplasm: Furthermore, we also performed a stratified analysis to assess the prognostic value of PVT1 in different subgroups, and observed that PVT1 was significantly associated with poor OS in patients with subgroups of residual tumor (R0), radiation therapy, no necrosis (0%), tumor size ≤5 cm, multinodular, female, and others histological type (Figure 2).