PVT1 and Familial prostate cancer: The oncogene role of PVT1 in cancers have been identified in multiple cancers including bladder cancer 41, nasopharyngeal carcinoma (NPC) 40, colorectal cancers (CRC) 37, non-small-cell lung cancer (NSCLC) 42, 43, clear cell renal cell carcinoma (ccRCC) 36, gastric cancer (GC) 44-46, head and neck squamous cell carcinoma (HNSCC)35, prostate cancer (PC) 34, esophageal squamous cell carcinoma (ESCC) 47, osteosarcoma 48, 49, hepatocellular carcinoma (HCC)50, 51, and pancreatic ductal adenocarcinoma (PDAC) 52.