Transcriptional levels of the all Nav α and β subunits were determined by real time-PCR in the six cases of endometrial cancer with pair tissues of carcinoma (EC) and adjacent nonneoplastic tissue (NE), the mitochondrial ribosomal protein L19 (MRPL19) was introduced as the reference gene to normalize Nav subtype gene expression 23. Here, MRPL19 is linked to carcinoma.