The most striking results came from the analysis of 13 DNA repair genes (MCM2, MLH1, CLK2, FANCG, EXO1, PARP1, CETN2, NEIL3, ALKBH3, POLI, POLD3, ERCC1 and FANCF) whose altered expression profile was significantly related to the survival of GC patients. This evidence concerns the gene MLH1 and gastric cancer.