SERINC5 and infection: Parental Jurkat T cells and the SERINC5(iHA/iHA), SERINC5(iHA/KO), and SERINC5(KO/KO) clones shared similar susceptibilities to infection by the vesicular stomatitis virus G protein (VSV-G)-pseudotyped, internal ribosome entry site (IRES)-green fluorescent protein (GFP)-expressing wild-type (WT) HIV-1 and HIV-1 Δnef mutant, as assessed by analysis of the percentage of GFP-positive cells at 2 days postinfection (Fig. 4A).