Another recent study of Yoxtheimer et al., examined OTP IHC expression on 50 FNA specimens, including 30 primary pulmonary NENs (eight TCs, six ACs, five LCNEC, and 11 SCLC) and 20 primary pancreatic NETs (Table 1) [20]. This evidence concerns the gene OTP and large cell neuroendocrine carcinoma.