Inflammatory cytokines, e.g., IL-1family members (IL-1α, IL-1β, IL-1Rα, IL-18, IL-33, IL-36, IL-37, and IL-38), are associated with the regulation of atherosclerosis, insulin resistance, and adipose tissue inflammation, all of which are common features of NAFLD [142,143]. The gene discussed is IL18; the disease is Insulin resistance.