The meta-analysis of eight studies [16,17,21,24,26,31,32,35] with available numeric data for this comparison (n = 1069 patients, 769 active SLE patients, 300 healthy controls) revealed that serum IP-10 in active SLE patients was significantly higher than the healthy controls (mean difference [MD] 153.9 pg/mL, 95% confidence interval [CI] 91.6 to 216.1, p < 0.001). The gene discussed is CXCL10; the disease is systemic lupus erythematosus.