PTGS2 and allergic asthma: Therefore, we investigated the effects of BPA exposure on (1) the cognitive function using the novel object recognition ability test and the hippocampal NMDA receptor expressions, and (2) neuroinflammation using inflammatory biomarkers such as IL-1β, TNF-α, cyclooxygenase-2 (COX2), ionized calcium binding adapter molecule (Iba)1, and behavior-related genes, such as the estrogen receptor (ER)α and oxytocin receptor (oxtr), in the hypothalamus of a mouse model with allergic asthma (AA).