APOE and Alzheimer disease: ApoE expression in CA1 was significantly greater in bexarotene-treated 3xTg-AD mice than in untreated 3xTg-AD mice (p < 0.05), but this disparity was not found in the dentate gyrus (DG), CA3, entorhinal cortex (Ent-Cx) or neocortex (Cx) (Fig 3 and S1 File).