In order to further confirm that the role of UCA1 in glioma cell invasion and migration involved in Wnt/β-catenin signaling, we treated the U87 and SHG139 cells with both UCA1 siRNA and LiCl (GSK3β inhibitor, which activates the Wnt/β-catenin signaling). Here, GSK3B is linked to central nervous system cancer.