DTX2 and colonic neoplasm: Consistent with the low expression of DTX2 and high expression of HSF2 in cluster2 (Figure 4D), DTX2 was highly expressed in docetaxel, cisplatin and PIK-93 resistant colon cancer cells (Figure 4F), while, HSF2 was highly expressed in docetaxel, cisplatin and PIK-93 sensitive colon cancer cells (Figure 4G).