IL18 and atherosclerosis: Inflammation is an important factor for the development of atherosclerosis, coronary plaques, and plaque rupture.1, 13, 14 A large number of inflammatory markers have been described, and IL‐18 has been reported associated with both presence of CV disease and clinical outcomes.6, 7 However, the exact role of these inflammatory mediators in ACS is complex and the importance of IL‐18 is only partly understood.