After infection, pulmonary cytokine and chemokine levels were lower in PKK ASO‐treated mice than in Ctrl ASO‐treated mice, albeit with a large inter‐individual variation; significant differences were found for IL‐6 and CXCL1 at 12 h after infection, and for IL‐6, IL‐1β, and CXCL2 at 36 h after infection. The gene discussed is IL6; the disease is infection.