A meta‐analysis demonstrated that the SNP rs9333555 of DNA polymerase eta (POLH) gene is related with higher melanoma risk.25 Polymorphisms (rs8305 and rs3218786) in DNA polymerase iota (POLI) gene have been previously reported to be correlated with lung cancer and prostate cancer.26, 27. This evidence concerns the gene POLI and Familial prostate cancer.