Kang et al 64 also reported that C-X-C chemokine receptor type 4 (CXCR4)-overexpressing MSC-derived exosomes could reduce infarct size, improve cardiac remodeling, and increase angiogenesis by activating the Akt signaling pathway following myocardial infarction. The gene discussed is CXCR4; the disease is myocardial infarction.