The expression of MMP11 in GC tumor tissues was also detected, and we found that MMP11 was significantly decreased in miR-139-exosome group compared with NC-exosome group (Fig. 6D); suggesting MMP11 was involved in the inhibitory effects of exosomal miR-139 on tumor growth and metastasis of GC cells. The gene discussed is MMP11; the disease is neoplasm.